Three-dimensional (3D) printing has emerged as a highly valuable tool to manufacture porous constructs. This has major advantages in, for example, tissue engineering, in which 3D scaffolds provide a microenvironment with adequate porosity for cell growth and migration as a simulation of tissue regeneration. In this study, we assessed the suitability of three cellulose nanofibrils (CNF) that were obtained through 2,2,6,6-tetramethylpyperidine-1-oxyl (TEMPO)-mediated oxidation. The CNFs were obtained by applying three levels of carboxylation, i.e., 2.5, 3.8, and 6.0 mmol sodium hypochlorite (NaClO) per gram of cellulose. The CNFs exhibited different nanofibrillation levels, affecting the corresponding viscosity and 3D printability of the CNF gels (0.6 wt%). The scaffolds were manufactured by micro-extrusion and the nanomechanical properties were assessed with nanoindentation. Importantly, fibroblasts were grown on the scaffolds and the expression levels of the marker genes, which are relevant for wound healing and proliferation, were assessed in order to reveal the effect of the 3D-scaffold microenvironment of the cells.
Alle gode ting er tre
Fra nanofiber i sårsalve til verdens høyeste trehus.
Interview in Svensk Papperstidning
The journal “Svensk Papperstidning” has recently published an interview with RISE PFI regarding RISE PFIs research within nanocelluloses (Svensk Papperstidning no. 2/22). Read more...
2021 TAPPI NanoDivision Mid-Career Award
Nanotechnology Division Mid-Career Award for research contributions related to the nanotechnology of renewable materials and contributions to the technical community. Read more...
Compouding world - May 2022
Development of sustainable biobased materials to replace fossil-based plastics. Read more...
Compouding world - May 2021
The BioComp project has been highlighted in Compounding World. We continue our efforts on assisting the industry with the implementation and realization of commercial products. Read more...
Interview in Compouding world - 2020
"Environmental concerns with plastic littering are motivating the development of sustainable biocomposites, where biobased plastics reinforced with lignocellulosic fibres are clear options. " Read more...
Testimonial in MANUNET
“Our innovation project can be divided into two specific biomedical developments. First, we focused on the development of an innovative prosthesis that improves the quality of life of vulnerable patients with cancer in the pelvic cavity. Secondly, we have produced oxygenated nanocelluloses for wound dressings.” Read more...
