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Examples of interdisciplinary research

RECENT COLLABORATIVE WORK


Polysaccharides and Structural Proteins as Components in Three-Dimensional Scaffolds for Breast Cancer Tissue Models: A Review


Breast cancer is the most common cancer among women, and even though treatments are available, efficiency varies with the patients. In vitro 2D models are commonly used to develop new treatments. However, 2D models overestimate drug efficiency, which increases the failure rate in later phase III clinical trials. New model systems that allow extensive and efficient drug screening are thus required. Three-dimensional printed hydrogels containing active components for cancer cell growth are interesting candidates for the preparation of next generation cancer cell models. Macromolecules, obtained from marine- and land-based resources, can form biopolymers (polysaccharides such as alginate, chitosan, hyaluronic acid, and cellulose) and bioactive components (structural proteins such as collagen, gelatin, and silk fibroin) in hydrogels with adequate physical properties in terms of porosity, rheology, and mechanical strength. Hence, in this study attention is given to biofabrication methods and to the modification with biological macromolecules to become bioactive and, thus, optimize 3D printed structures that better mimic the cancer cell microenvironment. Ink formulations combining polysaccharides for tuning the mechanical properties and bioactive polymers for controlling cell adhesion is key to optimizing the growth of the cancer cells.

Alle gode ting er tre

Fra nanofiber i sårsalve til verdens høyeste trehus.

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Interview in Svensk Papperstidning

The journal “Svensk Papperstidning” has recently published an interview with RISE PFI regarding RISE PFIs research within nanocelluloses (Svensk Papperstidning no. 2/22). Read more...


2021 TAPPI NanoDivision Mid-Career Award

Nanotechnology Division Mid-Career Award for research contributions related to the nanotechnology of renewable materials and contributions to the technical community. Read more...

Compouding world - May 2022

Development of sustainable biobased materials to replace fossil-based plastics. Read more...


Compouding world - May 2021

The BioComp project has been highlighted in Compounding World. We continue our efforts on assisting the industry with the implementation and realization of commercial products. Read more...


Interview in Compouding world - 2020

"Environmental concerns with plastic littering are motivating the development of sustainable biocomposites, where biobased plastics reinforced with lignocellulosic fibres are clear options. "  Read more...


Testimonial in MANUNET

“Our innovation project can be divided into two specific biomedical developments. First, we focused on the development of an innovative prosthesis that improves the quality of life of vulnerable patients with cancer in the pelvic cavity. Secondly, we have produced oxygenated nanocelluloses for wound dressings.” Read more...


Elicitors from food residues - LinkedIn

“Innovative solutions to waste streams in the wine and fruit juice industries have been developed in this project, extracting medium to high-added value mixtures that can be used as plant immune-system elicitors in green-houses and farms, with the potential to reduce the need for agrochemicals”, Read more...


Turning agricultural biowaste into high-value 3D-printing materials
Bagasse is an agro-industrial residue with major potential for several high-value products. Read more...


Surface-modified nanocellulose hydrogels for wound dressing. NanoWerk

Cellulose is a biopolymer consisting of long chains of glucose with unique structural properties whose supply is practically inexhaustible. It is found in the cell walls of plants where it serves to provide a supporting framework – a sort of skeleton. Nanocellulose from wood – i.e. wood fibers broken down to the nanoscale – is a promising nanomaterial with potential applications as a substrate for printing electronics, filtration, or biomedicine. Read more...